Mouzon may refer to:
- Places in France
- Mouzon, Ardennes, a commune in the Ardennes department
- Mouzon, Charente, a commune in the Charente department
- Mouzon (river) the Mouzon river in Ardennes and Lorraine, France
- People
- Alphonse Mouzon (1948–2016), American jazz fusion drummer and percussionist
- Henry Mouzon (1741–1807), an important officer under Francis Marion in the South Carolina militia during the American Revolution
- Wesley Mouzon (1927–2003), professional boxer
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