Murano is a surname. Notable people with the surname include:

• Elsa Murano (born 1959), American university president
• Jacopo Murano (born 1991), Italian footballer
• Maria Murano (1918–2009), French opera singer
• Yiya Murano (1930–2014), Argentine murderer

Murano (written: 村野 or 邑野) is also a Japanese surname. Notable people with the surname include:

• Masao Murano (村野 正夫, born 1935), Japanese ice hockey player
• Mia Murano (邑野 未亜, born 1986), Japanese model and actress
• Tetsutaro Murano (村野 鉄太郎, born 1929), Japanese film director
• Togo Murano (村野 藤吾, 1891–1984), Japanese architect