Computing

• Network Parameter Control in computer networks
• Non-deterministic polynomial-time complete
• Non-printing character

Electronics

• Neutral Point Clamped, an inverter topology

Medicine

• Nasopharyngeal carcinoma
• "Near point of convergence" or "no previous correction", optometric abbreviations
• Neural progenitor cell; see Notch signaling pathway
• Niemann–Pick disease, type C
  • NPC1, a protein involved in the disease
  • NPC2, a protein involved in the disease
• Nuclear pore complex, in molecular biology

Corporations

• National Petrochemical Company of Iran
• National Power Corporation, the Philippines
• Nauru Phosphate Corporation, Republic of Nauru
• Nevada Power Company, United States

Political organisations

• An abbreviation of Nationalist Party of China, an alias for the Kuomintang.
• National Peace Council, UK
• Nationalist People's Coalition, a political party in the Philippines
• National People's Congress, China
• National Petroleum Council (US)
• Northern People's Congress, a political party in Nigeria

Student organisations

• National Panhellenic Conference, of North American sororities
• National Postgraduate Committee, UK

Other organisations

see also under Sport, below

• National Press Club, several press clubs
• Niagara Parks Commission, Ontario, Canada
• Northern Provincial Council, Sri Lanka

Sport

• National Paralympic Committee
• National Physique Committee, a US bodybuilding organization
• National Provincial Championship (1976–2005), New Zealand rugby competition
• National Provincial Championship (2006–present), New Zealand rugby competition
• Non-playing captain of a team in contract bridge

Computer and video games

• Non-player character
  • NPC (meme), an Internet meme