Actors and entertainers

• Patrick Armand, French ballet dancer
• Patrick Brasca, Canadian–Taiwanese singer
• Patrick Cargill, British actor
• Pat Condell, English stand-up comedian
• Pat Corley, American actor
• Patrick Dempsey (born 1966), American actor
• Patrick Duffy, American actor
• Patrick Ellis (radio host) (1943–2020), American radio show host
• Patrick Nattawat Finkler (born 2003), Thai–German actor, singer, dancer, songwriter and model
• Patrick Fugit (born 1982), American actor
• Patrick Gower, New Zealand journalist
• Patrick Heusinger (born 1981), American actor
• Patrick J. Adams (born 1981), Canadian actor
• Patrick Macnee, English actor
• Patrick Magee, Irish actor
• Patrick McDonnell, Irish actor
• Patrick McGoohan (1928–2009), Irish-American actor
• Patrick Monahan, Irish comedian
• Patrick O'Connell, Irish actor
• Pat Paulsen (1927–1997), American comedian and satirist
• Pat Sajak, American game show host
• Patrick Stewart (born 1940), English actor
• Patrick Swayze (1952–2009), American actor
• Patrick Tam (actor) (born 1969), Hong Kong actor and singer
• Patrick Tang (born 1974), Hong Kong singer, actor, and television host
• Patrick Topaloff (1944–2010), French singer and actor
• Patrick Troughton (1920–1987), English actor
• Patrick Tse (born 1936), Hong Kong actor, producer, screenwriter and director
• Patrick Warburton (born 1964), American actor
• Patrick Waltz (1924–1972), American actor
• Patrick Wilson (born 1973), American actor and singer

Other

• Sean Patrick Flanery, American actor
• Sean Patrick Thomas, American actor
• Neil Patrick Harris, American actor

Authors

• Patrick, the pseudonym used by artist John Byrne (born 1940), Scottish playwright
• Patrick Cary (c. 1624–1658), English poet
• Pat Chapman, English food writer
• Padraic Colum (1881–1972), Irish author
• Patrick Cullinan (1932–2011), South African poet and biographer
• Patrick Delaforce, historian and British Army captain
• Patrick Jennings (born 1962), American children's book author
• Patrick Jones (born 1965), Welsh poet and playwright
• Patrick Lane (1939–2019), Canadian poet
• Patrick Modiano (born 1945), French novelist
• Patrick Pearse (1879–1916), Irish poet and nationalist
• Patrick O'Brian (1914–2000), English author and translator
• Patrick Süskind (born 1949), German writer and screenwriter

Musicians

• Pat Acuña (born 1986), American drummer, member of indie rock band Silent Old Mtns
• Patrick Alavi, German musician
• Pat Boone, American singer
• Patrick Brasca, Canadian-Taiwanese singer
• Patrick Carney (born 1980), American drummer, member of indie rock band The Black Keys
• Pat DiNizio (1955–2017), American songwriter, lead singer of the band The Smithereens
• Patrick Doyle, Scottish film composer
• Patrick Girondi, singer, composer
• Patrick Hernandez, French singer
• Patrick Lindner, German singer
• Pat Metheny, American jazz guitarist
• Steven Patrick Morrissey (born 1959), British singer
• Patrick Monahan (born 1969), American musician (rock band Train)
• Patrick "Pat" O'Brien, former lead guitarist for the death metal band Cannibal Corpse, former member for the heavy metal band Nevermore and a former touring musician with the thrash metal band Slayer
• Patrick Chukwuemeka Okogwu, known as Tinie Tempah, British rapper
• Patrick Simmons (born 1948), American guitarist and singer, founding member of the band The Doobie Brothers
• Patrick Stump (born 1984), American musician, lead singer and rhythm guitarist of the band Fall Out Boy
• Patrick Wilson (born 1969), American musician, drummer of the band Weezer
• Patrick Wolf (born 1983), English singer-songwriter

Politicians

• Patrick Dankwa Anin (1928-1999), Ghanaian politician
• Patrik Björck (born 1957), Swedish politician
• Patrick Blake (1846–1909), Canadian politician
• Patrick Boland, Irish politician
• Patrick Buchanan, American political commentator, author and politician
• Patrick Byrne, Irish politician
• Patrick Connor, Irish politician
• Patrick Donnelly, Irish politician
• Patrick Duffy, Irish politician
• Patrick Duncan, South African politician
• Patrik Engström (born 1968), Swedish politician
• Patrick F. Gill, American Representative
• Patrick Henry (1736–1799), American revolutionary figure
• Patrick Hetzel (born 1964), French Member of Parliament
• Patrick Hillery (1923–2008), the sixth President of Ireland (1976–1990)
• Patrick J. Kennedy, former United States congressman
• Patrick Leonard, Irish politician
• Patrik Lundqvist (born 1984), Swedish politician
• Patrick Matibini (born 1959), Zambian politician and judge / current speaker of the national assembly 'parliament'
• Patrick Murphy, Irish politician
• Patrick Norton, Irish politician
• Patrick Palmer, Irish politician
• Patrick Pearse (aka Pádraig Pearse) (1879–1916), Irish activist and revolutionary
• Pat Roberts, American Senator from Kansas
• Pat Robertson, American preacher and political figure
• Patrick Lipton Robinson, Jamaican U.N. judge
• Patrick Tierney, Irish politician
• Patrick Vahoe (born 1970), Solomon Islands politician
• Patrick Vans, Scottish judge
• Patrick Vanse (1655–1733), Scottish MP
• Levy Patrick Mwanawasa (1948-2008), Former President of the Republic of Zambia

Religious figures

• Saint Patrick, Christian saint
• Patrick Duggan (bishop), Roman Catholic Bishop of Clonfert in Ireland

Sportspeople

• Patrick, the working name of professional wrestler Don Harris
• Patrik Andersson, Swedish football player
• Patrick Baldassarre (born 1986), Swiss basketball player
• Pat Cummins, Australian Cricketer
• Patrick Bamford, English football player
• Pat Barry (born 1979), American kickboxer and mixed martial artist
• Pat Batteaux (born 1978), American football player
• Patrick Battiston (born 1957), French footballer
• Patrik Berger, Czech football player
• Patrik Berglund, Swedish ice hockey player
• Pat Boller (born 1972), American ice hockey coach and executive
• Paddy Bradley, Irish Gaelic football player
• Patrick Burris, American judoka and two-time Olympian
• Patrick Cain, American football player
• Pat Calathes (born 1985), Greek-American basketball player
• Pat Cash, Australian tennis player
• Patrick Chan (born 1990), Canadian figure skater
• Patrick Chung, American football player
• Patrick Dangerfield, Australian football player
• Patrick Eaves, American-Canadian ice hockey player
• Pat Elflein, American football player
• Pat Elzie, American-German basketball coach and former player
• Patrick Ewing, American basketball player
• Patrick Faber (field hockey), Dutch field hockey player
• Patrick Fernandes (born 1993), Cape Verdean footballer
• Pat Freiermuth (born 1998), American football player
• Patrik Gunnarsson (born 2000), Icelandic footballer
• Pádraig Harrington, Irish professional golfer
• Patrick Heuscher, Swiss volleyball player
• Patric Hörnqvist, Swedish ice hockey player
• Patrekur Jóhannesson, Icelandic handball coach
• Patrick Kane, professional ice hockey player
• Patrick Kluivert, Dutch football player
• Patrick Kühl, German swimmer
• Patrik Kühnen, German tennis player
• Patrik Laine, Finnish ice hockey player
• Patrick Laird (born 1995), American football player
• Patrick Lam (born 1983), Hong Kong equestrian
• Patrick Larkins (1860–1918), American baseball player
• Patrick Lewis, American football player
• Pat Mahomes, American baseball player; father of Patrick Mahomes II
• Patrick Mahomes II, American football player
• Patrick Matt, Liechtensteiner cyclist
• Pat Matzdorf, American athlete
• Patrick Mazeika (born 1993), American baseball player
• Patrick Mboma (born 1970), Cameroonian football player
• Pat McAfee (born 1987), American football player and Sports analyst
• Patrick McEnroe, American tennis player
• Patrick McGuirk (born 1967), American football player
• Patrick Mekari (born 1997), American football player
• Patrick Miller (basketball) (born 1992), American basketball player in the Israeli Basketball Premier League
• Patty Mills, Australian basketball player←
• Patrick Morris (American football) (born 1995), American football player
• Pat Mountain, Welsh football player
• Patrick O'Connell (1887–1959), Irish footballer
• Pat O'Connor (disambiguation), multiple people
• Pat O'Hanlon (born 1991), Australia Rugby League player
• Patrick Owomoyela (born 1979), German footballer
• Patrick Pedersen (born 1991), Danish footballer
• Patrick Queen (born 1999), American football player
• Patrick Rafter, Australian tennis player
• Patrick Rakovsky, German football player
• Patrick Ramsey, American football player
• Patrick Ricard (American football) (born 1994), American football player
• Pat Richards (born 1981), Australian Rugby League player
• Patrick Rowe (born 1969), American football player
• Patrick Roy, Canadian ice hockey goaltender
• Pat Ryan (born 1955), American football player
• Patrick Sandoval, American baseball player
• Patrick Scales (American football), American football player
• Patrick Schmollinger, Austrian swimmer
• Patrick da Silva, Brazilian football player
• Patrik Sjöberg, Swedish high jumper
• Pat Spillane, Irish Gaelic footballer
• Patrick Surtain (born 1976), American football player
• Patrick Surtain II (born 2000), American football player
• Pat Tillman (born 1976), American football player and Army Ranger
• Patrick Vahe (born 1996), American football player
• Patrick Veszpremi, Australian rules footballer
• Patrick Vieira, Senegalese-born French football player
• Patrik Virta (born 1996), Finnish ice hockey player
• Patrick Vörös (born 1993), Canadian professional wrestler
• Patrick Willis (born 1985), American football player

Other

• H.I.H. Prince Patrick Ali of Iran
• Patrick Abercrombie, English town planner
• Patrick Bokanowski, a French filmmaker
• Patrick Tracy Burris (1967–2009), American spree killer
• Patrick Carr (disambiguation), multiple people
• Patrick Critton, American former teacher and the first successful aircraft hijacker
• Patrick E. Crago, American medical researcher
• Patrick Wood Crusius (born 1998), suspect in the 2019 El Paso shooting
• Patrick Degorce (born 1969), French hedge fund manager
• Pat Finucane (1949–1989), Irish lawyer
• Patrick Fitzgerald, American Attorney
• Patrick Flanagan, American inventor
• Patrick Gaffney (disambiguation), multiple people
• Patrik Gardesten, Swedish officer
• Patrick de Gayardon (1960–1998), French skydiver, skysurfer and BASE jumper
• Patrick Gordon, Imperial Russian Army general
• Patrick Graham (disambiguation), multiple people
• Patrick Harvey (disambiguation), multiple people
• Patrick Hemingway, son of author Ernest Hemingway
• Patrick Hitler, half-nephew of Adolf Hitler
• Patrick Jeffrey, American diver
• Patrick Kearney (born 1939), prolific American serial killer, rapist, and necrophile
• Pat Kenny, Irish broadcaster
• Patrick Kielty, Irish comedian and television presenter
• Pat Kiernan, television news anchor
• Patrick Kong, Hong Kong film director and screenwriter
• Patrick Lee (Chinese businessman), Chinese business magnate
• Patrick Anson, 5th Earl of Lichfield (1939–2005; also known as Patrick Lichfield), photographer
• Patrick Lin (chef), Hong Kong Senior Executive Chef
• Patrick Lin (cinematographer), Hong Kong–born cinematographer and layout artist
• Patrick Lung (1934-2014), Hong Kong film director
• Patrick Lynch (disambiguation), multiple people
• Patrick Mackay (born 1952), British serial killer
• Patrick McGuinness (disambiguation), multiple people
• Sir Patrick Moore, English astronomer
• Patrick Moore (born 1947), founder member of Greenpeace
• Patrick Nogueira, Brazilian murderer serving three life sentences plus 25 years in Spain
• Pat O'Brien, radio and television personality
• Patrick Russell (disambiguation), multiple people
• Patrick Rechner, Canadian Captain taken hostage working as a UN observer in Bosnia
• Patrick "Spaz" Spaziante, American comic book artist
• Patrick Stritch, Irish photographer from Fermoy, County Cork, best known for his picture of Irish Republican Army general, Liam Lynch
• Patrick Swift (1927–1983), painter
• Patrick Tam (film director) (born 1948), Hong Kong film director and film editor
• Patrick Whelan (1893–1916), Irish Volunteer, KIA during the Easter Rising of 1916
• Patrick Taylor (disambiguation), multiple people
• Patrick Theodore (born 1985), Footwear Designer (Indonesian)
• Patrick Warren (born 1985) British missing person since 1996
• Patrick Williams (disambiguation), multiple people
• Patrick Yau, Hong Kong film director and assistant director