Patti is an Italian surname. Notable people with the surname include:
- Adelina Patti (1843–1919), Italian-French opera singer
- Antonino da Patti, Sicilian priest
- Archimedes Patti (1913 – 1998), lieutenant colonel in the United States Army and an Office of Strategic Services
- Carlotta Patti (c. 1840 – 1889), Italian operatic soprano and older sister to famed soprano Adelina Patti
- Carmelo Patti (c. 1934 – 2016), Italian businessman with close links to the Mafia
- Cathy Gentile-Patti (born 1962), American para-alpine skier
- Dino Patti Djalal (born 1965), former Indonesian ambassador to the United States
- Ercole Patti (1903–1976), Italian author, dramatist, screenwriter and journalist
- Guesch Patti (born 1946), French singer
- Luis Patti (born 1952), Argentine politician and a former senior police officer
- Tom Patti (born 1963), American businessman and politician
See also
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