The 2006 Oklahoma Sooners football team represented the University of Oklahoma in the college football season of 2006-2007, winning the Big 12 Conference Championship. The team was coached by Bob Stoops, led on offense by quarterback Paul Thompson, and played their homes games at Gaylord Family Oklahoma Memorial Stadium.

The previous year's team did not quite reach to the expectations that head coach Bob Stoops has set for his teams. The Sooners ended the previous season with eight wins and four losses, third in the Big 12 South standings and 22nd in both the Associated Press and USA Today polls.

This season saw the Sooners re-emerge to the forefront of college football. The season began when the starting quarterback and an offensive lineman were kicked off the team the day before fall practice started. They lost two of their first five games including a controversial loss to the Oregon Ducks and a loss to the defending national champion Texas Longhorns. They followed those losses with eight consecutive wins. The Sooners won their fourth conference championship under Bob Stoops to make 40 conference championships total. They played Boise State University in the Fiesta Bowl and lost in what many consider one of the "greatest" bowl games of all time. The Sooners' defense again ended the season nationally ranked finishing number one is several categories in the conference. Following the season, Adrian Peterson was selected seventh overall in the 2007 NFL Draft. In addition to Peterson, Rufus Alexander and C. J. Ah You were also drafted into the National Football League (NFL).

• We need a playoff. — Bernie Machen, president of the University of Florida who supported creating a play-off for NCAA Division I-A
• I like to believe that my best hits border on felonious assault. — former Ohio State Buckeyes defensive back Jack Tatum, on the fierce quality of his play
• If anything goes bad, I did it. If anything goes semi-good, we did it. If anything goes really good, then you did it. That's all it takes to get people to win football games for you. — University of Alabama Crimson Tide head coach Paul "Bear" Bryant, on his motivational techniques
• When people used to see Wake Forest on the schedule, they used a pen to mark down a `W.' We're at the point now where we at least make them use a pencil. — Wake Forest head coach Jim Grobe

• ... that the Harvard Crimson football team (home stadium pictured) has won 12 national championships and is the eighth winningest team in NCAA Division I football history?
• ... that American football running back Keith Elias graduated from Princeton University with 21 Princeton Tigers records and 4 National Collegiate Athletic Association I-AA records?
• ... that Vanderbilt's "Blonde Bear" supervised the ransacking of black households in the 1946 Columbia Race Riot?
• ... that Native American football player Peter Hauser has been credited with throwing the first spiral pass?

• ... that the Yale Bulldogs football team (mascot pictured) has won 27 national championships and ranks second in wins in college football history?
• ... that Michigan's All-American 60-minute man Tom Johnson was the second African-American player for the Green Bay Packers?
• ... that Deputy National Security Advisor Denis McDonough played for Hall of Fame football coach John Gagliardi at Saint John's University?
• ... that the Wittenberg Tigers from Springfield, Ohio, have won more games than any other Division III college football team?