Proffitt is a surname. Notable people with the name include:
- Cy Proffitt (1911–1996), American basketball player
 - Ethel Maude Proffitt Stephenson (née Ethel Maude Proffitt) (1895—1982), American lawyer
 - Frank Proffitt (1913–1965), Appalachian old-time banjoist and performer
 - Kathryn Linda Haycock Proffitt (born 1951), American diplomat
 - Michael Proffitt, Scottish chief editor for the Oxford English Dictionary
 - Morgan Proffitt (born 1994), American soccer player
 - Paine Proffitt (born 1972), American-born artist living in England
 - Shane Profitt, American musician
 - Stanley Proffitt (1910–1999), English cricketer
 - Steve Proffitt, American radio journalist
 - Tommy Proffitt (1927–2023), British boxer
 
Other uses
- Proffitt's, an American department store chain based in Alcoa, Tennessee, from 1919 to 2006
 - Thacher Proffitt & Wood, an American law firm headquartered in New York City from 1848 to 2008
 
See also
- All pages with titles containing Proffitt
 - Proffit (disambiguation)
 - Profit (disambiguation)
 
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