Pyrene may refer to:
- Pyrene, a chemical compound.
 - Carbon tetrachloride, pyrene is the brand name used by the Pyrene Manufacturing Company for Carbon tetrachloride.
 - Pyrene (mythology), consort of Ares and the mother of Cycnus in Greek mythology
 - Pyrene, a Celtic city near the sources of the Danube mentioned by Herodotus: see Heuneburg
 - The Pyrene Company Limited, a manufacturer of firefighting equipment
 - The Pyrene Building, Golden Mile (Brentford), a noted former Pyrene Company factory in London, England in the Art Deco style
 - Pyrene (gastropod), a genus of sea snails from the family Columbellidae
 - Pyrena, a kind of nutlet
 - Pyrenees, a mountain range between France and Spain
 
See also
- Pyrenoid, a stone-like structure within the chloroplast of hornworts and some algae
 
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