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Quintessence, or fifth essence, may refer to:

Cosmology

• Aether (classical element), in medieval cosmology and science, the fifth element that fills the universe beyond the terrestrial sphere
• Quintessence (physics), a hypothetical form of dark energy, postulated to explain the accelerating expansion of the universe

Literature

• Quintessence: Basic Readings from the Philosophy of W. V. Quine, essays by Willard Van Orman Quine
• Quintessence: The Quality of Having It, a 1983 book by Betty Cornfeld and Owen Edwards
• Works by Lawrence M. Krauss:
  • The Fifth Essence, a 1989 book
  • Quintessence: The Search for Missing Mass in the Universe, a 2000 book
• Quintessence, a 2013 science fiction book by David Walton

Media companies

• Quintessence Films, a film production company
• Quintessence International Publishing Group, a publishing company founded in Berlin, Germany

Music

• Quintessence Records, a budget label

Video games

• "Quintessence: The Blighted Venom", a game by Freebird Games

Proper names

• Quintessence (horse), a thoroughbred racer (1900–1917)
• The Quintessence, a DC Comics group of mutually consulting cosmic beings: see resp. Ganthet section

Other uses

• Quintessence (restaurant), a Michelin 3-star Japanese French fusion restaurant in Shinagawa, Japan.

See also

• Quintessenz, an Austrian on-line civil liberties advocacy organization
• Quintessons, fictional characters from the Transformers franchise
• Fifth Element (disambiguation)