SASA may refer to:
- Saginaw Arts and Sciences Academy, a small public high school and middle school for developmentally advanced children in Saginaw, Michigan
- Scottish Agricultural Science Agency, formerly an executive agency of the Scottish Executive Environment and Rural Affairs Department
- Serbian Academy of Sciences and Arts, the most prominent academic institution in Serbia
- Slovenian Academy of Sciences and Arts, the national academy of Slovenia
- Solvent Accessible Surface Area, a measure of the solvent accessible surface area of a biomolecule
- Scouts South Africa, formerly known as the Scout Association of South Africa
- South African Speleological Association, a caving organization
- Student Achievement and School Accountability Programs, a program in the U.S. Department of Education
- Martín Miguel de Güemes International Airport, Argentina (ICAO code: SASA)
- SASA Impact FC, a Canadian women's soccer team
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