SCIC may refer to:
- Directorate-General for Interpretation, abbreviated after its former French name Service Commun Interprétation-Conférences
- Société Centrale Immobilière de la Caisse des dépôts, the predecessor of real-estate investment company Icade
- the Supreme Council of Islamic Courts, another name for the Islamic Courts Union
- State Capital Investment Corporation, a state-owned company in Vietnam
- Scic, an Italian road bicycle racing team 1969–1979
- Spinal Cord Injury Centre
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