Sis or SIS may refer to:
People
- Michael Sis (born 1960), American Catholic bishop
 
Places
- Sis (ancient city), historical town in modern-day Turkey, served as the capital of the Armenian Kingdom of Cilicia.
 - Kozan, Adana, the current name of the Armenian town of Sis in Cilicia, Turkey
 - Sis, Armenia, a village in Armenia
 - Sis, Azerbaijan, a village in the Republic of Azerbaijan
 - Sis, Iran, a city in East Azerbaijan, Iran
 - Sis, Kurdistan, a village in Kurdistan, Iran
 - Sis Rural District (Shabestar County), East Azerbaijan province, Iran
 - Sis Rural District (Dehgolan County), Kurdistan province, Iran
 - Mountains of Sis, a range of the Pre-Pyrenees
 
Intelligence
- Schengen Information System, in Europe
 - Security Information Service, Czech domestic information intelligence agency known as BIS
 - Secret Intelligence Service, UK intelligence agency, also known as MI6
 - Australian Secret Intelligence Service, Australia’s national intelligence service
 - Canadian Security Intelligence Service, Canada's national intelligence service
 - New Zealand Security Intelligence Service, an intelligence agency of the New Zealand government
 - Finnish Security Intelligence Service, the intelligence agency of Finland in charge of national security
 - Slovenská informačná služba, Slovak Intelligence Service
 - Special Intelligence Service, a secret FBI intelligence agency operating in South America during World War II
 - Signals Intelligence Service, the former United States Army codebreaking division
 - Information and Security Service of the Republic of Moldova, the principal intelligence agency of Moldova.
 - Serviço de Informações de Segurança, a Portuguese intelligence agency
 - Survey of India Service, formerly the Great Trigonometric Survey
 - Special Investigation Section, a tactical detective and surveillance unit of the Los Angeles Police Department
 - Signals Intelligence Section, involved with the Magic project during World War II
 
Businesses
- Silicon Integrated Systems, an electronics manufacturing company
 - Sports Information Services, a news service company
 - Siemens IT Solutions and Services, a service provider which is part of Siemens AG headquarters
 - SIS (motorbikes), a Portuguese manufacturer of motorcycles
 
Schools
China
- Shekou International School, in Shekou
 - Singapore International School, in Hong Kong
 - South Island School, in Hong Kong
 
United States
Other schools
- SIS Swiss International School, a group of 15 private day schools in Switzerland, Germany and Brazil
 - McGill University School of Information Studies, Canada
 - School of International Studies of the Dresden University of Technology, Germany
 - Singapore International School Mumbai, India
 - Surabaya International School, Indonesia
 - Seoul International School, South Korea
 - Stockholm International School, Sweden
 - Sharjah Indian School, United Arab Emirates
 
Other organizations
- Sisters in Islam, an organization based in Malaysia
 - Swedish Institute for Standards
 - Specialized Information Services, a division of the United States National Library of Medicine
 - State Information Service, official media and public relations apparatus of the Egyptian state
 
Information processing
- SIS (file format), Symbian OS filename extension
 - Short integer solution problem, a problem in lattice-based cryptography
 - Single-instance storage, information-storage space-saving mechanism
 - Strategic information system, a part of corporate strategy
 - Student information system, a software application for education establishments to manage student data
 - Sequential Importance Sampling
 
Biological sciences
- Small intestinal submucosa, transplantation tissue
 - Second-impact syndrome, synergy in concussions
 - Sex in space, an area of biological research
 
Healthcare
- Saline infusion sonography, a test used to diagnose uterine polyps
 - Shoulder impingement syndrome, tendinitis of the shoulder
 
Technologies
- Selective inverted sink, frost protection device
 - Safety instrumented system or safety instrumentation system
 - Space Infrastructure Servicing, a robotic spacecraft for in-space refueling of communication satellites
 - Sequential infiltration synthesis, a method to infiltrate polymers to create inorganic-organic hybrid materials
 
Other uses
- SIS (group), South Korean girl group founded 2017
 - SiS (TV series), a morning talk show
 - SIS, a 2008 television film directed by John Herzfeld
 - Supervised injection site
 - MS Sis, car ferry
 - Singular isothermal sphere profile, a simple density distribution used in astronomy
 - Silicon monosulfide, chemical formula SiS
 
See also
- Sister, a female sibling
 - Sissy, a pejorative term for a boy or man who violates or does not meet the traditional male gender role
 - Shimano Index Shifting, bicycle transmission design
 - Single-image stereogram
 - Superconductor-insulator-superconductor tunnel junction
 - Swedish National Board of Institutional Care, abbreviated SiS
 - SIS 18, an accelerator at the GSI Helmholtz Centre for Heavy Ion Research
 - Special Investigations Section (disambiguation)
 - Cis (disambiguation)
 - Ciss (disambiguation)
 
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