Sir William Russell, 1st Baronet may refer to:
- Sir William Russell, 1st Baronet, of Chippenham (died 1654), English politician
- Sir William Russell, 1st Baronet, of Wytley (c. 1602 – 1669), English politician
- Sir William Russell, 1st Baronet, of Charlton Park (1773–1839), Scottish physician
See also
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