Spagnuolo (Italian: [spaɲˈɲwɔːlo], Neapolitan: [ʃpaɲˈɲwoːlə]) is an Italian surname, meaning literally "Spanish or "from Spain" and may refer to:
- Giovanni Spagnuolo, Italian engineer
- Giuseppe Crespi, nicknamed "Lo Spagnuolo", Italian painter
- Jason Spagnuolo, Australian soccer player
- Steve Spagnuolo, Defensive coordinator of Kansas City Chiefs of the National Football League
See also
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