- Flavius Syagrius (consul 381), Roman consul in 381
 - Afranius Syagrius, Roman consul in 382.
 - Syagrius (430 – 486 or 487) Roman official of the Gallo-Roman enclave of Soissons after the collapse of Western Roman empire.
 - Saint Syagrius of Autun (died 600), bishop of Autun
 - Syagrius of Verona, a bishop of Verona c. 360.
 - Syagrius, a beetle genus
 
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