van Eeghen is a surname. Notable people with the surname include:
- Isabella Henriette van Eeghen (1913–1996), Dutch historian
- Esmée van Eeghen (1918-1944), Dutch resistance fighter in World War II
- Mark van Eeghen (born 1952), American football player
- Hester van Eeghen (1958–2021), Dutch designer
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