Vitale is an Italian surname which derives from the Latin word Vita meaning 'life'. The name may refer to:
- Ami Vitale (b. 1971), American photojournalist
- Bobby Vitale (b. 1965), American porn film actor
- Carol Vitale (b. 1948), American model and television hostess; Playboy Playmate 1974
- Carson Vitale (b. 1988), Canadian baseball coach
- Dick Vitale (b. 1939), American basketball broadcaster
- Eletise Leafa Vitale (contemporary), Samoan government minister who plotted and carried out an assassination
- Falaniko Vitale (contemporary), American mixed martial arts fighter
- Frank Vitale, President and CEO of Maryland University of Integrative Health
- Gaetano Vitale (b. 2001), Italian footballer
- Giordano Vitale (1633–1711), Italian mathematician
- Ida Vitale (b. 1923), Uruguayan poet, Miguel de Cervantes Prize 2018
- Joe Vitale (musician) (b. 1949), American multi-instrument musician
- Joe Vitale (ice hockey) (born 1985), American ice hockey player
- John Vitale (American football) (1965–2000), American college football player
- John Vitale (mobster) (1909–1982), American mobster of the St. Louis crime family
- Joseph Vitale (politician) (b. 1954), American politician from New Jersey; state legislator
- Leafa Vitale (contemporary), Samoan government minister who plotted an assassination
- Leonardo Vitale (1941–1984), Sicilian Mafia member who became an informant
- Lito Vitale (b. 1961), Argentine musician
- Louie Vitale (1932–2023), American Roman Catholic priest; cofounder of the Nevada Desert Experience
- Luigi Vitale (b. 1987), Italian professional football player
- Marcello Vitale (contemporary), Italian musician
- Milly Vitale (1932–2006), Italian actress
- Raoul Gregory Vitale (1928–2003), Syrian musicologist
- Russell Vitale (b. 1992), Sicilian American rapper
- Salvatore Vitale (b. 1947), American mobster; underboss of the Bonanno crime family of New York
- Thomas Vitale (contemporary), American television network executive
- Vito Vitale (b. 1958), Sicilian Mafia member
See also
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