William Jacobs may refer to:
- W. W. Jacobs (1863–1943), short story writer
- William H. Jacobs (1831–1882), Wisconsin legislator and banker
- Will Jacobs (born 1955), American comics writer
- William Elmer Jacobs, baseball player
- William Jacobs (producer) (1887–1953), film producer
- William R. Jacobs Jr. (born 1955), professor of microbiology, immunology and genetics
See also
- William Jacob (disambiguation)
- All pages with titles containing William Jacobs
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