William O'Callaghan may refer to:
- William O'Callaghan (Irish Army officer) (1921–2015), Irish Army officer
- William Frederick Ormonde O'Callaghan (1852–1877), Irish MP
- William O'Callaghan (politician) (died 1967), Irish senator
- Bill O'Callaghan (1868–1946), hurler
See also
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