William Penn (1644–1718) was the English founder of Pennsylvania

William Penn may also refer to:

People

• William Penn (Royal Navy officer) (1621–1670), English admiral under Cromwell and Charles II and the father of William Penn
• William Penn Jr. (1681–1720), eldest surviving son of William Penn, founder of Pennsylvania
• William Penn (athlete) (1883–1943), American tug-of-war competitor
• William Evander Penn (1832–1895), Texas Baptist evangelist and minister
• William S. Penn (born 1949), mixed-race Nez Perce author and English professor at Michigan State University
• William F. Penn (1871–1934), black physician in Atlanta, Georgia
• William Penn (pen name), pen name used by activist Jeremiah Evarts (1781–1831) in his essays against Indian removal
• William Penn (cricketer) (1849–1921), Kent county cricketer

Schools and societies

• William Penn University, private liberal arts university in Iowa
• William Penn Middle School, part of the Pennsbury School District in Bucks County, Pennsylvania
• William Penn High School (Delaware) in New Castle, Delaware
• William Penn High School (North Carolina) in High Point, North Carolina
• William Penn High School (Philadelphia) in Philadelphia, Pennsylvania

Other

• William Penn (cigar brand), type of machine-made cigars manufactured by General Cigar Company
• USS Tecumseh (SSBN-628), submarine that was going to be named the USS William Penn
• a train operated by Amtrak as part of the Clocker service
• William Penn (Calder), an 1894 bronze statue by Alexander Milne Calder
• William Penn, Texas, an unincorporated community in Washington County, Texas