Young's syndrome
Other namesAzoospermia sinopulmonary infections

Young's syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young syndrome, is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced male fertility.[1][2][3] In individuals with this syndrome the functioning of the lungs is usually normal but the mucus is abnormally viscous. The reduced fertility (obstructive azoospermia) is due to functional obstruction of sperm transport down the genital tract at the epididymis, where the sperm is found in viscous, lipid-rich fluid.[3][4] The syndrome was named after Donald Young,[5] the urologist who first made observations of the clinical signs of the syndrome in 1972.[6] Possible causes include genetics, and exposure to mercury during childhood, but the cause is unknown.[2]

Causes

Young's syndrome is caused by helminthiasis where specific parasites are attacking the reproductive organs.[7]

See also

References

  1. ↑ Handelsman DJ, Conway AJ, Boylan LM, Turtle JR (January 1984). "Young's syndrome. Obstructive azoospermia and chronic sinopulmonary infections". N. Engl. J. Med. 310 (1): 3–9. doi:10.1056/NEJM198401053100102. PMID 6689737. S2CID 19418407.
  2. 1 2 Young syndrome at NIH's Office of Rare Diseases
  3. 1 2 Young's syndrome - General Practice Notebook
  4. ↑ Definition: Young syndrome from Online Medical Dictionary
  5. ↑ Young, M (January 2003). "Obituary of Donald Herron Young". BMJ. 326 (7382): 226. doi:10.1136/bmj.326.7382.226/g. PMC 1125087.
  6. ↑ Online Mendelian Inheritance in Man (OMIM): Young syndrome - 279000
  7. ↑ Blackwell, Aaron D.; Tamayo, Marilyne A.; Beheim, Bret; Trumble, Benjamin C.; Stieglitz, Jonathan; Hooper, Paul L.; Martin, Melanie; Kaplan, Hillard; Gurven, Michael (2015). "Helminth infection, fecundity, and age of first pregnancy in women". Science. 350 (6263): 970–972. doi:10.1126/science.aac7902. PMC 5953513. PMID 26586763.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.