糖蛋白激素α亚基

Glycoprotein hormones, alpha polypeptide; 绒毛膜促性腺激素，α多肽
	PDB rendering based on 1dz7.
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	1DZ7, 1E9J, 1FL7, 1HCN, 1HD4, 1HRP, 1QFW, 1XWD, 4AY9
标识
代号	CGA; CG-ALPHA; FSHA; GPHA1; GPHa; HCG; LHA; TSHA
扩展标识	遗传学：118850 鼠基因：88390 同源基因：587 GeneCards: CGA Gene
基因本体论描述
分子功能	· hormone activity; · protein binding;
细胞成分	· extracellular region;
生物过程	· thyroid hormone generation; · signal transduction; · cell-cell signaling; · positive regulation of cell proliferation; · gonad development; · peptide hormone processing; · positive regulation of cell migration; · thyroid gland development; · luteinizing hormone secretion; · cellular response to hormone stimulus; · cellular protein metabolic process; · positive regulation of transcription from RNA polymerase II promoter; · negative regulation of organ growth; · follicle-stimulating hormone secretion; · developmental growth;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体

糖蛋白激素α亚基（英語：，或称为绒毛膜促性腺激素α亚基，）是一个由人类基因CGA 编码的蛋白质[1]。

人体的四种糖蛋白激素--人绒毛膜促性腺激素（hCG）、黄体生成素（LH）、促卵泡激素（FSH）和促甲状腺激素（TSH）都是以同样的该α亚基和各自不同的β亚基组成的二聚体。[2]

此α链的92个氨基酸残基的序列为：

NH₂ - Ala - Pro - Asp - Val - Gln - Asp - Cys - Pro - Glu - Cys - Thr - Leu - Gln - Glu - Asn - Pro - Phe - Phe - Ser - Gln - Pro - Gly - Ala - Pro - Ile - Leu - Gln - Cys - Met - Gly - Cys - Cys - Phe - Ser - Arg - Ala - Tyr - Pro - Thr - Pro - Leu - Arg - Ser - Lys - Lys - Thr - Met - Leu - Val - Gln - Lys - Asn - Val - Thr - Ser - Glu - Ser - Thr - Cys - Cys - Val - Ala - Lys - Ser - Tyr - Asn - Arg - Val - Thr - Val - Met - Gly - Gly - Phe - Lys - Val - Glu - Asn - His - Thr - Ala - Cys - His - Cys - Ser - Thr - Cys - Tyr - Tyr - His - Lys - Ser - COOH

参考文献

Fiddes JC, Goodman HM. . J Mol Appl Genet. Oct 1982, 1 (1): 3–18. PMID 6286817.
. （原始内容存档于2010-12-05）.

延伸阅读

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糖蛋白激素α亚基引用了美国国家医学图书馆提供的資料，这些資料属于公共领域。

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[pmid6286817-1] Fiddes JC, Goodman HM. . J Mol Appl Genet. Oct 1982, 1 (1): 3–18. PMID 6286817.

[2] . （原始内容存档于2010-12-05）.