人類人工染色體
人類人工染色體(Human artificial chromosome,HAC)是一種小型染色體,可作為載體搭載一些基因,並作為人類細胞中額外的染色體(第47個),使這些基因表現於人類體內。此種人工染色體可載有約600到1000萬的鹼基對。HAC最早是發表於1997年。
參考文獻
- Formation of de novo centromeres and construction of first-generation human artificial microchromosomes (页面存档备份,存于) in Nature Genetics 15, 345 - 355 (1997) Harrington and Bokkelen et al.
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