早幼粒细胞白血病蛋白

· transcription coactivator activity
· protein binding
· zinc ion binding
· ubiquitin protein ligase binding
· SUMO binding
· protein homodimerization activity
· SMAD binding
· protein heterodimerization activity

· nucleoplasm
· nucleolus
· cytoplasm
· cytosol
· nuclear matrix
· PML body
· early endosome membrane
· nuclear membrane

· regulation of protein phosphorylation
· positive regulation of defense response to virus by host
· transcription, DNA-templated
· regulation of transcription, DNA-templated
· protein complex assembly
· protein targeting
· apoptotic process
· activation of cysteine-type endopeptidase activity involved in apoptotic process
· DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
· cell cycle arrest
· transforming growth factor beta receptor signaling pathway
· common-partner SMAD protein phosphorylation
· SMAD protein import into nucleus
· negative regulation of cell proliferation
· intrinsic apoptotic signaling pathway in response to DNA damage
· intrinsic apoptotic signaling pathway in response to oxidative stress
· response to UV
· response to gamma radiation
· regulation of calcium ion transport into cytosol
· viral process
· negative regulation of angiogenesis
· cytokine-mediated signaling pathway
· myeloid cell differentiation
· negative regulation of cell growth
· PML body organization
· positive regulation of histone deacetylation
· negative regulation of telomere maintenance via telomerase
· endoplasmic reticulum calcium ion homeostasis
· circadian regulation of gene expression
· negative regulation of translation in response to oxidative stress
· response to cytokine
· regulation of circadian rhythm
· intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
· entrainment of circadian clock by photoperiod
· proteasome-mediated ubiquitin-dependent protein catabolic process
· innate immune response
· cell fate commitment
· regulation of MHC class I biosynthetic process
· negative regulation of transcription, DNA-templated
· negative regulation of mitotic cell cycle
· retinoic acid receptor signaling pathway
· protein stabilization
· maintenance of protein location in nucleus
· defense response to virus
· negative regulation of telomerase activity
· positive regulation of apoptotic process involved in mammary gland involution
· interferon-gamma-mediated signaling pathway
· branching involved in mammary gland duct morphogenesis
· intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
· cellular response to interleukin-4
· cellular senescence
· extrinsic apoptotic signaling pathway
· negative regulation of viral release from host cell
· negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
· regulation of double-strand break repair