免疫佐剂
免疫佐剂(英語:)简称佐剂(英語:),是指与抗原同时或预先注射到动物体内,可非特异性地增强机体对该抗原的免疫应答的物质[1] ,所以又称为非特异性免疫增强剂。
在注射极少量抗原或低免疫原性抗原时,加入佐剂可以促进免疫应答的发生;佐剂一般有延长抗原持续性、加强共同刺激信号、增加局部发炎反应、刺激非特异性淋巴细胞增生的功能。
外部链接
- Recommendations for Use and Alternatives to Freund's Complete Adjuvant (页面存档备份,存于). University of Iowa
- Vaxjo: Comprehensive vaccine adjuvant database (页面存档备份,存于).
参考文献
- The Use of Conventional Immunologic Adjuvants in DNA Vaccine Preparations, by Shin Sasaki and Kenji Okuda. In D.B. Lowrie and R.G. Whalen (editors), DNA Vaccines: Methods and Protocols, Humana Press, 2000. ISBN 978-0-89603-580-5.
- DNA Vaccines: Methods and Protocols, D.B. Lowrie and R.G. Whalen, Humana Press, 2000. ISBN 978-0-89603-580-5.
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