组织蛋白酶W
组织蛋白酶W(英语:Cathepsin W)是一种在人体中由CTSW基因编码的蛋白质。[5][6][7]
组织蛋白酶W | |||||||||||||||||||||||||
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識別號 | |||||||||||||||||||||||||
别名 | CTSW;, LYPN, cathepsin W | ||||||||||||||||||||||||
外部ID | OMIM:602364 MGI:1338045 HomoloGene:37471 GeneCards:CTSW | ||||||||||||||||||||||||
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RNA表达模式 | |||||||||||||||||||||||||
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直系同源 | |||||||||||||||||||||||||
物種 | 人類 | 小鼠 | |||||||||||||||||||||||
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Ensembl | |||||||||||||||||||||||||
UniProt | |||||||||||||||||||||||||
mRNA序列 | |||||||||||||||||||||||||
蛋白序列 | |||||||||||||||||||||||||
基因位置(UCSC) | Chr 11: 65.88 – 65.88 Mb | Chr 19: 5.52 – 5.52 Mb | |||||||||||||||||||||||
PubMed查找 | [3] | [4] | |||||||||||||||||||||||
維基數據 | |||||||||||||||||||||||||
该基因编码的蛋白质是半胱氨酸组织蛋白酶肽酶C1家族的成员,是一种半胱氨酸蛋白酶组织蛋白酶,可能在T细胞溶细胞活性的机制或调节中具有特定功能。编码的蛋白质被发现与自然杀伤细胞和细胞毒性T细胞的内质网内的细胞膜有关。该基因的表达被白细胞介素2上调。[7]
参见
参考文献
- GRCh38: Ensembl release 89: ENSG00000172543 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000024910 - Ensembl, May 2017
- . National Center for Biotechnology Information, U.S. National Library of Medicine.
- . National Center for Biotechnology Information, U.S. National Library of Medicine.
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- Wex T, Levy B, Smeekens SP, Ansorge S, Desnick RJ, Bromme D. . Biochem Biophys Res Commun. Aug 1998, 248 (2): 255–61. PMID 9675123. doi:10.1006/bbrc.1998.8954.
- .
阅读
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- Wex T, Levy B, Wex H, Brömme D. . Biochem. Biophys. Res. Commun. 1999, 259 (2): 401–7. PMID 10362521. doi:10.1006/bbrc.1999.0700.
- Brown J, Matutes E, Singleton A, et al. . Leukemia. 1998, 12 (11): 1771–81. PMID 9823953. doi:10.1038/sj.leu.2401164 .
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