轉錄激活因子
轉錄激活因子(英文:Activator)是一種蛋白質轉錄因子,可增加一個基因或一組基因的轉錄。[1]轉錄激活因子被認為對基因表達具有積極的調控作用,因為它們具有促進基因轉錄的功能,在某些情況下是基因轉錄所必需的。[1][2][3][4]大多數激活因子是與增強子和啟動子近端元件結合的DNA結合蛋白。[1]與激活因子結合的DNA位點稱為“激活因子結合位點”。[3]激活因子與一般轉錄機制發生蛋白質相互作用的部分稱為“活化區”或“活化域”。[1]
參考資料
- Ma, Jun. . Protein & Cell. 2011, 2 (11): 879–888 [2021-03-17]. ISSN 1674-8018. PMC 4712173 . PMID 22180087. doi:10.1007/s13238-011-1101-7. (原始内容存档于2021-05-15) –PubMed.
- Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Morgan, David; Raff, Martin; Roberts, Keith; Walter, Peter. Sixth. New York, NY: Garland Science. 2015: 373–392 [2021-03-17]. ISBN 978-0-8153-4432-2. OCLC 887605755. (原始内容存档于2021-04-20).
- Madigan, Michael T; Bender, Kelly S; Buckley, Daniel H; Sattley, Matthew W; Stahl, David A. Fifteenth. NY, NY: Pearson. 2018: 174–179. ISBN 978-0-13-426192-8. OCLC 958205447.
- Griffiths, Anthony J.F.; Gelbart, William M.; Miller, Jeffrey H.; Lewontin, Richard C. . Modern Genetic Analysis. 1999 –NCBI (英语).
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