CD19

CD19
識別號
别名	CD19；, B4, CVID3, CD19 molecule
外部ID	OMIM：107265 MGI：88319 HomoloGene：1341 GeneCards：CD19
基因位置（人类）
染色体	16號染色體[1]
终止	28,939,342 bp[1]
基因位置（小鼠）
染色体	小鼠7号染色体[2]
终止	126,014,061 bp[2]
RNA表达模式
	查阅更多表达数据
基因本體
分子功能	• 血浆蛋白结合; • phosphatidylinositol-4,5-bisphosphate 3-kinase activity;
細胞組分	• integral component of membrane; • 细胞膜; • integral component of plasma membrane; • 外排體; • 膜; • external side of plasma membrane; • 大分子复合体; • 脂筏模型;
生物學過程	• cellular defense response; • cell surface receptor signaling pathway; • regulation of immune response; • positive regulation of release of sequestered calcium ion into cytosol; • phosphatidylinositol phosphate biosynthetic process; • B cell receptor signaling pathway; • regulation of complement activation; • positive regulation of protein kinase B signaling; • B-1 B cell differentiation; • B cell proliferation involved in immune response; • immunoglobulin mediated immune response; • B cell mediated immunity; • positive regulation of phosphatidylinositol 3-kinase activity; • antigen receptor-mediated signaling pathway; • regulation of B cell receptor signaling pathway; • regulation of B cell activation; • adaptive immune response; • immune system process;
	Sources:Amigo / QuickGO
直系同源
	930
	12478
	ENSG00000177455
	ENSMUSG00000030724
	P15391
	P25918
	NM_001178098; NM_001770; NM_001385732
	NM_009844; NM_001357091
	NP_001171569; NP_001761
	NP_033974; NP_001344020
	維基數據

CD19（cluster of differentiation 19，分化簇19，也称为“B淋巴细胞抗原CD19”，B-lymphocyte antigen CD19，“B淋巴细胞表面抗原B4”，CVID3）是一种细胞表面蛋白质，由人类基因 CD19 编码，是B淋巴细胞的主要标志物[5][6]。

参考文献

GRCh38: Ensembl release 89: ENSG00000177455 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000030724 - Ensembl, May 2017
. National Center for Biotechnology Information, U.S. National Library of Medicine.
. National Center for Biotechnology Information, U.S. National Library of Medicine.
Schroeder HW, Rich RR. . 4th. London. 2013: 47–51. ISBN 978-0-7234-3691-1. OCLC 823736017.
Scheuermann RH, Racila E. . Leukemia & Lymphoma. August 1995, 18 (5–6): 385–97. PMID 8528044. doi:10.3109/10428199509059636.

外部链接

Mouse CD Antigen Chart
Human CD Antigen Chart
Human CD19 genome location and CD19 gene details page in the UCSC Genome Browser.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000177455 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030724 - Ensembl, May 2017

[3] . National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] . National Center for Biotechnology Information, U.S. National Library of Medicine.

[Schroeder_2013-5] Schroeder HW, Rich RR. . 4th. London. 2013: 47–51. ISBN 978-0-7234-3691-1. OCLC 823736017.

[Scheuermann_1995-6] Scheuermann RH, Racila E. . Leukemia & Lymphoma. August 1995, 18 (5–6): 385–97. PMID 8528044. doi:10.3109/10428199509059636.