儿茶酚-O-甲基转移酶抑制药

兒茶酚-O-甲基轉移酶抑制劑COMT抑制劑(英語: Catechol-O-methyl transferase inhibitorCOMT inhibitor)是抑制儿茶酚-O-甲基转移酶的藥物。這個酶參與神经递质的降解。COMT抑制劑用於治療帕金森氏症

一些製劑:恩他卡朋,[1] tolcapone,[2] opicapone 以及 nitecapone

参考资料

  1. Nissinen E; Nissinen H; Larjonmaa H; et al. . J Neural Transm. September 2005, 112 (9): 1213–1221. PMID 15614425. doi:10.1007/s00702-004-0262-4.
  2. Giakoumaki SG, Roussos P, Bitsios P. . Neuropsychopharmacology. June 2008, 33 (13): 3058–3068. PMID 18536698. doi:10.1038/npp.2008.82.


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