CYP24A1

CYP24A1
已知的結構
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	3K9V、3K9Y
識別號
别名	CYP24A1；, CP24, CYP24, HCAI, P450-CC24, cytochrome P450 family 24 subfamily A member 1, HCINF1
外部ID	OMIM：126065 MGI：88593 HomoloGene：68094 GeneCards：CYP24A1
相關疾病
	多发性硬化症[1]
基因位置（人类）
染色体	20號染色體[2]
终止	54,173,986 bp[2]
基因位置（小鼠）
染色体	小鼠2号染色体[3]
终止	170,339,065 bp[3]
RNA表达模式
	查阅更多表达数据
基因本體
分子功能	• iron ion binding; • 25-hydroxycholecalciferol-24-hydroxylase activity; • 金屬離子結合; • monooxygenase activity; • heme binding; • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; • oxidoreductase activity; • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity;
細胞組分	• 细胞膜; • 核质; • 線粒體; • 细胞核; • mitochondrial outer membrane;
生物學過程	• response to vitamin D; • vitamin D metabolic process; • vitamin metabolic process; • osteoblast differentiation; • vitamin D catabolic process; • vitamin D receptor signaling pathway;
	Sources:Amigo / QuickGO
直系同源
	1591
	13081
	ENSG00000019186
	ENSMUSG00000038567
	Q07973
	Q64441
	NM_000782; NM_001128915
	NM_009996
	NP_000773; NP_001122387
	NP_034126
	維基數據

细胞色素 P450 24A1（英語：，缩写CYP24A1）也被称为维生素D₃ 24-羟化酶（，EC 1.14.15.16），是细胞色素P450超家族的一员，由CYP24A1基因编码，是定位于线粒体内膜的单加氧酶，能催化骨化三醇（1,25-二羟维生素D₃）的24号位的羟基化[6]。

参考文献

.
GRCh38: Ensembl release 89: ENSG00000019186 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000038567 - Ensembl, May 2017
. National Center for Biotechnology Information, U.S. National Library of Medicine.
. National Center for Biotechnology Information, U.S. National Library of Medicine.
. （原始内容存档于2010-12-05）.

外部链接

醫學主題詞表（MeSH）：CYP24A1+protein,+human
Human CYP24A1 genome location and CYP24A1 gene details page in the UCSC Genome Browser.

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[1] .

[refGRCh38Ensembl-2] GRCh38: Ensembl release 89: ENSG00000019186 - Ensembl, May 2017

[refGRCm38Ensembl-3] GRCm38: Ensembl release 89: ENSMUSG00000038567 - Ensembl, May 2017

[4] . National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] . National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-6] . （原始内容存档于2010-12-05）.