DUX4

DUX4
識別號
别名	DUX4；, DUX4L, double homeobox 4
外部ID	OMIM：606009 GeneCards：DUX4
基因位置（人类）
染色体	4號染色體[1]
终止	190,185,942 bp[1]
基因本體
分子功能	• DNA结合; • transcription cis-regulatory region binding; • 血浆蛋白结合; • RNA polymerase II cis-regulatory region sequence-specific DNA binding; • DNA-binding transcription activator activity, RNA polymerase II-specific; • sequence-specific double-stranded DNA binding;
細胞組分	• 核膜; • 细胞核; • 核质; • 核仁; • 细胞质基质; • 高尔基体;
生物學過程	• negative regulation of G0 to G1 transition; • regulation of transcription, DNA-templated; • transcription, DNA-templated; • negative regulation of cell population proliferation; • positive regulation of transcription by RNA polymerase II; • 细胞凋亡; • transcription by RNA polymerase II; • multicellular organism development;
	Sources:Amigo / QuickGO
直系同源
	100288687
	无数据
	ENSG00000260596; ENSG00000283949
	无数据
	Q9UBX2
	无数据
	NM_001205218; NM_001278056; NM_001293798; NM_001306068; NM_001363820
	无数据
	NP_001280727; NP_001292997; NP_001350749
	无数据
	維基數據

双同源异型框4（英語：，简称DUX4）基因位于染色体4q35亚端粒区域的D4Z4重复序列。D4Z4重复序列的长度具多态性，在第10号染色体也发现类似D4Z4重复序列。

参考文献

GRCh38: Ensembl release 89: ENSG00000260596、ENSG00000283949 - Ensembl, May 2017
. National Center for Biotechnology Information, U.S. National Library of Medicine.

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