加布里尔-科尔曼重排反应

加布里尔-科尔曼重排反应(Gabriel–Colman rearrangement)指酞酰亚胺钾(1)与氯乙酸缩合为酞酰亚胺基乙酸酯(2),然后用强碱处理,得到取代异喹啉(3)。[1][2][3][4]

加布里尔-科尔曼重排
加布里尔-科尔曼重排

参见

参考资料

  1. Gabriel, S.; Colman, J. Ber. 1900, 33, 980 & 996 & 2630.
  2. Gabriel, S.; Colman, J. Ber. 1902, 35, 2421.
  3. Allen, C. F. H. Chem. Rev. 1950, 47, 275. (综述)
  4. Hill, J. H. M. J. Org. Chem. 1965, 30, 620.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.