| (2,3-dihydroxybenzoyl)adenylate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.58 | ||||||||
| CAS no. | 122332-73-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a (2,3-dihydroxybenzoyl)adenylate synthase (EC 2.7.7.58) is an enzyme that catalyzes the chemical reaction ATP + 2,3-dihydroxybenzoate diphosphate + (2,3-dihydroxybenzoyl)adenylate.[1]
Thus, the two substrates of this enzyme are ATP and 2,3-dihydroxybenzoate, whereas its two products are diphosphate and (2,3-dihydroxybenzoyl)adenylate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:2,3-dihydroxybenzoate adenylyltransferase. This enzyme is also called 2,3-dihydroxybenzoate-AMP ligase. This enzyme participates in biosynthesis of siderophore group nonribosomal.
References
- ↑ Rusnak F, Faraci WS, Walsh CT (August 1989). "Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product". Biochemistry. 28 (17): 6827–6835. doi:10.1021/bi00443a008. PMID 2531000.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.