(S)-β-Macrocarpene synthase
Identifiers
EC no.5.5.1.17
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

(S)-β-macrocarpene synthase (EC 5.5.1.17, TPS6, TPS11) is an enzyme with systematic name (S)-β-macrocarpene lyase (decyclizing).[1] This enzyme catalyses the following chemical reaction

(S)-β-bisabolene (S)-β-macrocarpene

The synthesis of (S)-beta-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps.

References

  1. Köllner TG, Schnee C, Li S, Svatos A, Schneider B, Gershenzon J, Degenhardt J (July 2008). "Protonation of a neutral (S)-beta-bisabolene intermediate is involved in (S)-β-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11". The Journal of Biological Chemistry. 283 (30): 20779–88. doi:10.1074/jbc.m802682200. PMC 3258946. PMID 18524777.
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