Singles
2021 Amex-Istanbul Challenger II
Champion	James Duckworth
Runner-up	Wu Tung-lin
Score	6–4, 6–2

Arthur Rinderknech was the defending champion^[1] but chose not to defend his title.

James Duckworth won the title after defeating Wu Tung-lin 6–4, 6–2 in the final.

Seeds

Draw

Finals

	Semifinals							Final
	1	James Duckworth	69	6	6
		Quentin Halys	711	3	4
								1	James Duckworth	6	6
									Wu Tung-lin	4	2
		Borna Gojo	4	6	4
		Wu Tung-lin	6	3	6

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	J Duckworth	7	6
		L Giustino	5	1				1	J Duckworth	6	6
		A Müller	6	6					A Müller	3	2
	Q	N Chappell	4	2											1	J Duckworth	6	6
	WC	S Ağabigün	4	6	4											H Grenier	3	3
		H Grenier	6	3	6				H Grenier	6	6
		A Kuznetsov	64	1				6	E Donskoy	4	4
	6	E Donskoy	77	6																		1	J Duckworth	69	6	6
	4	Y Uchiyama	6	3	6																		Q Halys	711	3	4
		H Moriya	3	6	3			4	Y Uchiyama	3	6	6
	Q	Christopher Heyman	3	6	6			Q	C Heyman	6	3	4
		A Arnaboldi	6	2	4										4	Y Uchiyama	5	2
		B Tomic	0	1												Q Halys	7	6
		Q Halys	6	6					Q Halys	3	6	6
		T Fabbiano	5	2				7	I Marchenko	6	2	2
	7	I Marchenko	7	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	LL	G Blancaneaux	4	77	6
	Q	L Lokoli	6	65	1			LL	G Blancaneaux	6	7
		C-h Tseng	6	2	6				C-h Tseng	3	5
		R Marcora	1	6	4										LL	G Blancaneaux	66	4
		E Tiurnev	5	6	0											B Gojo	78	6
		E Karlovskiy	7	4	6				E Karlovskiy	1	77	65
		B Gojo	6	3	6				B Gojo	6	64	77
	3	DE Galán	4	6	2																		B Gojo	4	6	4
	5	M Polmans	6	6																			T-l Wu	6	3	6
	WC	K Kırcı	3	2				5	M Polmans	2	6	1
		T Ito	3	2					T-l Wu	6	3	6
		T-l Wu	6	6												T-l Wu	6	6
	Q	A Šetkić	6	6											Q	A Šetkić	3	2
	WC	VV Cornea	4	2				Q	A Šetkić	4	6	7
		M Ebden	4	6	1			2	R Albot	6	3	5
	2	R Albot	6	1	6

References

External links

• Main draw
• Qualifying draw