Singles
2021 Biella Challenger VI
Champion	Thanasi Kokkinakis
Runner-up	Enzo Couacaud
Score	6–3, 6–4

Juan Pablo Varillas was the defending champion^[1] but chose not to defend his title.

Thanasi Kokkinakis won the title after defeating Enzo Couacaud 6–3, 6–4 in the final.

Seeds

Draw

Finals

	Semifinals							Final
	Q	Tomás Martín Etcheverry	1	7	4
	3	Enzo Couacaud	6	5	6
								3	Enzo Couacaud	3	4
									Thanasi Kokkinakis	6	6
		Thanasi Kokkinakis	6	4	6
	2	Zhang Zhizhen	2	6	3

Top half

	First round							Second round							Quarterfinals							Semifinals
	1/WC	P Lorenzi	0	65
	Q	TM Etcheverry	6	77				Q	TM Etcheverry	4	77	4
		F Meligeni Alves	6	6					F Meligeni Alves	6	60	0r
		J Clarke	3	3											Q	TM Etcheverry	6	6
		T Lamasine	5	6	1											F Mena	3	2
		D Kuzmanov	7	4	6				D Kuzmanov	2	78	1
		F Mena	6	6					F Mena	6	66	6
	7	J Menezes	3	4																		Q	TM Etcheverry	1	7	4
	3	E Couacaud	6	6																		3	E Couacaud	6	5	6
		T Kamke	4	2				3	E Couacaud	77	5	6
	Q	T van Rijthoven	6	6				Q	T van Rijthoven	64	7	2
	Q	Omar Giacalone	2	2											3	E Couacaud	6	65	6
		A Collarini	6	6											8	B Fratangelo	1	77	3
		M Copil	2	1					A Collarini	6	62	0r
		C İlkel	2	4				8	B Fratangelo	1	77	3
	8	B Fratangelo	6	6

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	A Bolt	79	1	3
	WC	S Napolitano	67	6	6			WC	S Napolitano	3	4
		D Istomin	6	2	3				T Kokkinakis	6	6
		T Kokkinakis	3	6	6											T Kokkinakis	6	77
		R Cid Subervi	5	3											4	A Müller	4	61
	Q	R Bonadio	7	6				Q	R Bonadio	0	64
		M Viola	6	3	1			4	A Müller	6	77
	4	A Müller	4	6	6																		T Kokkinakis	6	4	6
	5	D Popko	2	6	62																	2	Zh Zhang	2	6	3
		T-S Kwiatkowski	6	1	77				T-S Kwiatkowski	6	77
		E Benchetrit	4	4					U Blanch	4	63
		U Blanch	6	6												T-S Kwiatkowski	4	65
		M Krueger	4	3											2	Zh Zhang	6	77
	WC	F Cobolli	6	6				WC	F Cobolli	6	4	2
		B Gojo	3	6	2			2	Zh Zhang	4	6	6
	2	Zh Zhang	6	4	6

References

• Main draw
• Qualifying draw