Singles
2021 Engie Open Andrézieux-Bouthéon 42
Champion	Harmony Tan
Runner-up	Jaqueline Cristian
Score	3–6, 6–2, 6–1

Ysaline Bonaventure was the defending champion, but chose not to participate.^[1]

Harmony Tan won the title, defeating Jaqueline Cristian in the final, 3–6, 6–2, 6–1.

Seeds

Draw

Finals

	Semifinals							Final
	Q	Urszula Radwańska	3	1
		Jaqueline Cristian	6	6
									Jaqueline Cristian	6	2	1
								WC	Harmony Tan	3	6	6
	WC	Harmony Tan	6	6
	Q	Kathinka von Deichmann	1	0

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	O Dodin	6	6
	Q	S Bandecchi	3	3				1	O Dodin	3	4
		L Pattinama Kerkhove	63	6	4			Q	U Radwańska	6	6
	Q	U Radwańska	77	2	6										Q	U Radwańska	6	6
	Q	S Djoubri	3	1												L Küng	4	1
		C Bucșa	6	6					C Bucșa	1	4
		L Küng	6	7					L Küng	6	6
	6	T Korpatsch	2	5																		Q	U Radwańska	3	1
	3	S Vögele	6	5	6																		J Cristian	6	6
	Q	D Marcinkēviča	4	7	2			3	S Vögele	66	2
		LI Paar	6	6					LI Paar	78	6
		Ç Büyükakçay	3	4												LI Paar	6	2	1
		J Cristian	5	6	6											J Cristian	1	6	6
	WC	D Parry	7	4	2				J Cristian	2	77	6
	WC	E Jacquemot	4	60				8	C Tauson	6	64	3
	8	C Tauson	6	77

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	5	T Martincová	5	6	6
	Q	F Di Sarra	7	4	0			5	T Martincová	4	67
	Q	G Desperrier	3	1				WC	H Tan	6	79
	WC	H Tan	6	6											WC	H Tan	6	6
	PR	Jia Lu	65	4											4	K Zavatska	0	1
	JE	V Jiménez Kasintseva	77	6				JE	V Jiménez Kasintseva	1	6	2
		G Gatto-Monticone	4	1				4	K Zavatska	6	3	6
	4	K Zavatska	6	6																		WC	H Tan	6	6
	7	V Tomova	6	6																		Q	K von Deichmann	1	0
	WC	A Hesse	3	2				7	V Tomova	0	4
	Q	K von Deichmann	6	6				Q	K von Deichmann	6	6
		X You	4	4											Q	K von Deichmann	7	6
		M Di Giuseppe	4	4											2	A-L Friedsam	5	4
	Q	R Šramková	6	6				Q	R Šramková	3	1
		I de Vroome	3	7	2			2	A-L Friedsam	6	6
	2	A-L Friedsam	6	5	6

References

• Main Draw