Singles
2022 Challenger de Santiago
Champion	Hugo Dellien
Runner-up	Alejandro Tabilo
Score	6–3, 4–6, 6–4

Sebastián Báez was the defending champion^[1] but chose not to defend his title.

Hugo Dellien won the title after defeating Alejandro Tabilo 6–3, 4–6, 6–4 in the final.

Seeds

Draw

Finals

	Semifinals							Final
	5	Tomás Martín Etcheverry	3	77	4
	3	Hugo Dellien	6	63	6
								3	Hugo Dellien	6	4	6
								2	Alejandro Tabilo	3	6	4
	4	Juan Pablo Varillas	66	1
	2	Alejandro Tabilo	78	6

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	J Lehečka	6	6
	Q	M Martineau	3	2				1	J Lehečka	6	3	6
		S Rodríguez Taverna	2	1					G Oliveira	3	6	3
		G Oliveira	6	6											1	J Lehečka	4	3
	WC	D Fernández Flores	3	1											5	TM Etcheverry	6	6
		C Ugo Carabelli	6	6					C Ugo Carabelli	1	6	5
	Q	E Furness	5	2				5	TM Etcheverry	6	4	7
	5	TM Etcheverry	7	6																		5	TM Etcheverry	3	77	4
	3	H Dellien	2	77	6																	3	H Dellien	6	63	6
		P Cachin	6	64	1			3	H Dellien	6	6
		R Olivo	6	6					R Olivo	3	4
	WC	Ignacio Becerra	2	0											3	H Dellien	6	6
	Q	H Casanova	1	6	2											J de Jong	3	3
	Q	P Jubb	6	2	6			Q	P Jubb	5	3
		J de Jong	6	77					J de Jong	7	6
	8	T Barrios Vera	1	60

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	JI Londero	6	77
		A Collarini	0	65				6	JI Londero	77	2	5
		M Pucinelli de Almeida	6	3	6				M Pucinelli de Almeida	65	6	7
		GA Olivieri	3	6	3											M Pucinelli de Almeida	5	2
	LL	D Dutra da Silva	4	2											4	JP Varillas	7	6
	Q	JB Torres	6	6				Q	JB Torres	1	3
		TA Tirante	4	3				4	JP Varillas	6	6
	4	JP Varillas	6	6																		4	JP Varillas	66	1
	7	N Jarry	6	63	3																	2	A Tabilo	78	6
		V Kopřiva	1	77	6				V Kopřiva	6	4	7
		F Mena	3	4					N Kicker	4	6	5
		N Kicker	6	6												V Kopřiva	2	6	3
	Q	Facundo Juárez	2	77	1										2	A Tabilo	6	4	6
		G Lama	6	64	6				G Lama	1	2
	WC	Daniel Antonio Núñez	5	0				2	A Tabilo	6	6
	2	A Tabilo	7	6

References

External links

• Main draw
• Qualifying draw