4-Thiouridine
Names
Preferred IUPAC name
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.034.291
EC Number
  • 237-735-3
MeSH Thiouridine
UNII
  • InChI=1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1
    Key: ZLOIGESWDJYCTF-XVFCMESISA-N
  • C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O
Properties
C9H12N2O5S
Molar mass 260.26 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

4-Thiouridine is an atypical nucleotide formed with the 4-thiouracil base found in transfer RNA (tRNA).[1] Its biosynthesis has been determined.[2]

References

  1. ↑ Alberts, Bruce (18 November 2014). Molecular biology of the cell (Sixth ed.). New York, NY. p. 337. ISBN 978-0-8153-4432-2. OCLC 887605755.{{cite book}}: CS1 maint: location missing publisher (link)
  2. ↑ Park, Chung-Min; Weerasinghe, Laksiri; Day, Jacob J.; Fukuto, Jon M.; Xian, Ming (2015). "Persulfides: Current knowledge and challenges in chemistry and chemical biology". Molecular BioSystems. 11 (7): 1775–1785. doi:10.1039/c5mb00216h. PMC 4470748. PMID 25969163.


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