ALDH1B1
Identifiers
AliasesALDH1B1, ALDH5, ALDHX, aldehyde dehydrogenase 1 family member B1
External IDsOMIM: 100670 MGI: 1919785 HomoloGene: 115470 GeneCards: ALDH1B1
Orthologs
SpeciesHumanMouse
Entrez

219

72535

Ensembl

ENSG00000137124

ENSMUSG00000035561

UniProt

P30837

Q9CZS1

RefSeq (mRNA)

NM_000692

NM_028270

RefSeq (protein)

NP_000683

NP_082546

Location (UCSC)Chr 9: 38.39 – 38.4 MbChr 4: 45.8 – 45.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aldehyde dehydrogenase X, mitochondrial is an enzyme that in humans is encoded by the ALDH1B1 gene.[5][6]

Function

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000137124 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035561 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hsu LC, Chang WC (Jul 1991). "Cloning and characterization of a new functional human aldehyde dehydrogenase gene". The Journal of Biological Chemistry. 266 (19): 12257–65. doi:10.1016/S0021-9258(18)98890-3. PMID 2061311.
  6. 1 2 "Entrez Gene: ALDH1B1 aldehyde dehydrogenase 1 family, member B1".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.