Ackles is a surname. Notable people with the surname include:
- Bob Ackles (1938–2008), Canadian football executive
- David Ackles (1937–1999), American singer-songwriter
- David Ackles (album), self-titled album
- George Ackles (born 1967), American professional basketball player
- Jensen Ackles (born 1978), American television actor
- Jill Ackles, American television director
- Margie Ackles (1939–2019), American figure skater
- Stephen Ackles (1961–2023), Norwegian vocalist, pianist, and songwriter
See also
- Other uses
- ACLs, acronym for access-control lists
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