| Bacteroidales-1 RNA | |
|---|---|
 Consensus secondary structure of Bacteroidales-1 RNAs | |
| Identifiers | |
| Symbol | Bacteroidales-1 |
| Rfam | RF01693 |
| Other data | |
| RNA type | sRNA |
| Domain(s) | Bacteroidales |
| PDB structures | PDBe |
The Bacteroidales-1 RNA motif is a conserved RNA structure identified by bioinformatics.[1] It has been identified only in bacteria within the order (biology) Bacteroidales. Its presumed length is marked by a promoter on one end that conforms to an alternate consensus sequence that is common in the phylum Bacteroidota, and its 3′ end is indicated by predicted transcription terminators.[2] It is often located downstream of a gene that encodes the L20 ribosomal subunit, although it is unclear whether there is a functional reason underlying this apparent association.[1]
Bacteroidales-1 RNA motif has been reported as a 6S RNA homologue by a report of Bacteroides thetaiotaomicron transcriptome map.[3] The existence of small product RNAs (pRNAs) that rescue sequestered RNA polymerases, validated 6S RNA-mediated regulation of transcriptional activity.
See also
References
- 1 2 Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
- ↑ Bayley DP, Rocha ER, Smith CJ (December 2000). "Analysis of cepA and other Bacteroides fragilis genes reveals a unique promoter structure". FEMS Microbiol. Lett. 193 (1): 149–154. doi:10.1111/j.1574-6968.2000.tb09417.x. PMID 11094294.
- ↑ Ryan, Daniel; Jenniches, Laura; Reichardt, Sarah; Barquist, Lars; Westermann, Alexander J. (2020-07-16). "A high-resolution transcriptome map identifies small RNA regulation of metabolism in the gut microbe Bacteroides thetaiotaomicron". Nature Communications. 11 (1): 3557. doi:10.1038/s41467-020-17348-5. ISSN 2041-1723. PMC 7366714. PMID 32678091.