C1QTNF4 (gene)

C1QTNF4
Identifiers
Aliases	C1QTNF4, CTRP4, ZACRP4, C1q and tumor necrosis factor related protein 4, C1q and TNF related 4
External IDs	OMIM: 614911 MGI: 1914695 HomoloGene: 12134 GeneCards: C1QTNF4
Gene location (Human)
Chr.	Chromosome 11 (human)
End	47,594,411 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	90,720,869 bp
RNA expression pattern
	Top expressed in
	superior frontal gyrus; ; nucleus accumbens; ; putamen; ; caudate nucleus; ; Brodmann area 9; ; temporal lobe; ; amygdala; ; hippocampus proper; ; hypothalamus; ; substantia nigra;
	Top expressed in
	superior frontal gyrus; ; olfactory bulb; ; hippocampus proper; ; spermatid; ; cerebellar cortex; ; spermatocyte; ; testicle; ; neural tube; ; mesencephalon; ; hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine activity; molecular function;
Cellular component	extracellular region; extracellular space;
Biological process	regulation of signaling receptor activity; positive regulation of interleukin-6 production; positive regulation of interleukin-6-mediated signaling pathway; positive regulation of NIK/NF-kappaB signaling; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	114900
	67445
	ENSG00000172247; ENSG00000284838
	ENSMUSG00000040794
	Q9BXJ3
	Q8R066
	NM_031909
	NM_026161
	NP_114115
	NP_080437
	Wikidata
View/Edit Human	View/Edit Mouse

C1q and tumor necrosis factor related protein 4 is a protein that in humans is encoded by the C1QTNF4 gene. ^[5]

References

Li Q, Wang L, Tan W, Peng Z, Luo Y, Zhang Y, Zhang G, Na D, Jin P, Shi T, Ma D, Wang L (2011). "Identification of C1qTNF-related protein 4 as a potential cytokine that stimulates the STAT3 and NF-κB pathways and promotes cell survival in human cancer cells". Cancer Lett. 308 (2): 203–14. doi:10.1016/j.canlet.2011.05.005. PMID 21658842.

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