| Coenzyme F420-0:L-glutamate ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.3.2.31 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Coenzyme F420-0:L-glutamate ligase (EC 6.3.2.31, CofE-AF, MJ0768, CofE) is an enzyme with systematic name L-glutamate:coenzyme F420-0 ligase (GDP-forming).[1][2] This enzyme catalyses the following chemical reaction
In some instances, this enzyme is fused with a coenzyme F420-1:gamma-L-glutamate ligase domain, so that the produced coenzyme F420-1 is quickly ligated to coenzyme F420-2.
References
- ↑ Li H, Graupner M, Xu H, White RH (August 2003). "CofE catalyzes the addition of two glutamates to F420-0 in F420 coenzyme biosynthesis in Methanococcus jannaschii". Biochemistry. 42 (32): 9771–8. doi:10.1021/bi034779b. PMID 12911320.
- ↑ Nocek B, Evdokimova E, Proudfoot M, Kudritska M, Grochowski LL, White RH, Savchenko A, Yakunin AF, Edwards A, Joachimiak A (September 2007). "Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases". Journal of Molecular Biology. 372 (2): 456–69. doi:10.1016/j.jmb.2007.06.063. PMC 2678844. PMID 17669425.
External links
- Coenzyme+F420-0:L-glutamate+ligase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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