A desmolase is any of various enzymes that catalyze the formation or destruction of carbon-carbon bonds within a molecule. These enzymes play a significant role in cellular respiration and in fermentation.[1] Desmolases are involved in steroidogenesis.

Examples of desmolases are:

  • Cholesterol side-chain cleavage enzyme, also called 20,22-desmolase; converts cholesterol to pregnenolone.
  • 17,20-Desmolase, also called CYP17A1 or 17α-hydroxylase; converts pregnenolone to 17α-hydroxypregnenolone, progesterone to 17α-hydroxyprogesterone, and corticosterone to aldosterone.
  • Diacetyl desmolase is added to beer late in the brewing process to remove diacetyl flavor that may have accumulated during processing.[2]

See also

References

  1. ↑ Wallerstein, Leo (1939). "Enzyme Preparations from Microorganisms: Commercial Production and Industrial Application". Industrial & Engineering Chemistry. 31 (10): 1218–1224. doi:10.1021/ie50358a012.
  2. ↑ Gutcho, Marcia Halpern (1969). Alcoholic Malt Beverages, 1969. Food Processing Reviews #7. Park Ridge, New Jersey: Noyes Development Corporation. p. 221. ISBN 978-0-8155-0282-1.
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