Edward John Wherry III (known professionally as John Wherry) is an American immunologist. He is the Richard and Barbara Schiffrin President's Distinguished Professor and department chair of Systems Pharmacology and Translational Therapeutics at the University of Pennsylvania. He is also the director of the Penn Institute for Immunology.[1]

E. John Wherry III
Academic background
Alma materPenn State University
Thomas Jefferson University
Emory University
Doctoral advisorLaurence Eisenlohr
Academic work
DisciplineImmunology
InstitutionsUniversity of Pennsylvania
Wistar Institute
Websitehttps://www.med.upenn.edu/wherrylab/

Education

Wherry received his B.S. degree in science from The Pennsylvania State University in 1993 and his Ph.D. in immunology from Thomas Jefferson University in 2000.[2] He completed his thesis on the effect of epitope density on CD8+ cell priming under the mentorship of Laurence "Ike" Eisenlohr.[3][4]

Academic posts

Wherry continued on to a postdoctoral fellowship with Rafi Ahmed at Emory University from 2000 to 2004.[5] After completing his postdoc, he joined The Wistar Institute as an assistant professor where he remained until 2010. He then joined the department of Microbiology at the University of Pennsylvania's Perelman School of Medicine. He served as the chair of the Immunology Graduate Group (IGG) from 2011 to 2013 and remains on the IGG Executive Committee. In 2012 he was appointed as director of the Institute for Immunology (IFI).[6] Wherry was named the inaugural Richard and Barbara Schiffrin President's Distinguished Professor in 2017.[7] A year later, Wherry was appointed as chair of the Systems Pharmacology and Translational Therapeutics department.[8]

Research

Wherry's research has focused on the field of T cell exhaustion, elucidating mechanisms that attenuate T cell responses during chronic infections and cancer. His discoveries include characterizing several immunological checkpoints and T cell states that can be targeted to re-invigorate exhausted T cells. Wherry's lab has played a prominent role in understanding the concept of human immune health using high-dimensional, integrative, translational immunology approaches.[9]

Awards and honors

  • 2018: Stand Up To Cancer Phillip A. Sharp Award[10]
  • 2016: Cancer Research Institute's Frederick W. Alt Award for New Discoveries in Immunology[11]
  • 2014 & 2016: Highly Cited Research and Rising Star by Thomson/Reuters ISI
  • 2014: "World's Most Influential Scientific Minds" Award by Thomson Reuters[12]
  • 2014: Dr. Wherry received the distinguished Alumni Award from the Thomas Jefferson University Graduate School of Biomedical Sciences[13]
  • 2007: "America's Young Innovators-37 under 36" by the Smithsonian Magazine[14]
  • 2006: New Scholar in Aging award from the Ellison Medical Foundation[15]

References

  1. ↑ "Wherry Lab". The Trustees of the University of Pennsylvania. Retrieved 2020-12-13.
  2. ↑ "E. John Wherry, PhD". The Trustees of the University of Pennsylvania. Retrieved December 13, 2020.
  3. ↑ Wherry, PhD (April 25, 2013). "Distinguished Alumni Award Lecture". Jefferson Digital Commons. Thomas Jefferson University. Retrieved December 13, 2020.
  4. ↑ "2000 Commencement for Jefferson Medical College and College of Graduate Studies". Jefferson Digital Commons. Thomas Jefferson University. June 9, 2000. Retrieved December 13, 2020.
  5. ↑ "Molecular basis of t cell exhaustion: Insights for immunotherapy". Cell Symposia: Cancer, Inflammation, and Immunity. Elsevier Inc. 2017. Retrieved December 13, 2020.
  6. ↑ "Molecular basis of t cell exhaustion: Insights for immunotherapy". Cell Symposia: Cancer, Inflammation, and Immunity. Elsevier Inc. 2017. Retrieved December 13, 2020.
  7. ↑ "E. John Wherry: Richard and Barbara Schiffrin President's Distinguished Professor". University of Pennsylvania Almanac. The University of Pennsylvania Almanac. January 10, 2017. Retrieved December 13, 2020.
  8. ↑ "Immunologist Named Chair of Systems Pharmacology". Penn Medicine News. Penn Medicine. July 23, 2018. Retrieved December 13, 2020.
  9. ↑ Jameson, MD, PhD, J. Larry (June 26, 2018). "Appointment of E. John Wherry, PhD, as Chair of the Department of Systems Pharmacology and Translational Therapeutics". Perelman School of Medicine. Retrieved December 13, 2020.{{cite web}}: CS1 maint: multiple names: authors list (link)
  10. ↑ "Stand Up To Cancer Encourages "Innovation in Collaboration" through Grants to Research Teams". Stand Up to Cancer. Entertainment Industry Foundation. March 28, 2018. Retrieved December 13, 2020.
  11. ↑ "Frederick W. Alt Award". Cancer Research Institute. Retrieved December 13, 2020.
  12. ↑ "The World's Most Influential Scientific Minds 2014" (PDF). Thomson Reuters. Reuters/Tony Gentile. April 2014. Retrieved December 13, 2020.
  13. ↑ Wherry, PhD (April 25, 2013). "Distinguished Alumni Award Lecture". Jefferson Digital Commons. Thomas Jefferson University. Retrieved December 13, 2020.
  14. ↑ "Molecular basis of t cell exhaustion: Insights for immunotherapy". Cell Symposia: Cancer, Inflammation, and Immunity. Elsevier Inc. 2017. Retrieved December 13, 2020.
  15. ↑ Kirk, Margaret O. (2006). "Preparing for the next flu pandemic--manmade or natural" (PDF). Summer 2006 FOCUS. The Wistar Institute. Retrieved December 13, 2020.
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