Eric Vivier
Born
Clamart. France
Scientific career
FieldsImmunology

Eric Vivier is a French professor of immunology at Aix-Marseille and hospital practitioner[1] at Marseille Public University Hospital. He is also Chief Scientific Officer at Innate Pharma,[2] coordinator of the Marseille Immunopôle immunology cluster,[3]  and president of the Paris-Saclay Cancer Cluster, the first biocluster selected by the French government as part of the France 2030 program.[4][5]

Biography

Vivier was born in Clamart, France.[6] He graduated from the Ecole Nationale Vétérinaire de Maisons-Alfort and received his doctoral degree in immunology from Paris XI University. He began his postdoctoral training as a Fogarty International Center Research Fellow at Harvard Medical School with Paul J. Anderson and Stuart F. Schlossman (the Dana-Farber Cancer Institute).[7][8]

He joined Aix-Marseille University as a professor at the Centre d'Immunologie de Marseille-Luminy (CIML) in 1993, becoming its director in 2008[9] until 2017.[2] Vivier is one of four immunologists whose research led to the creation of the biotech company Innate-Pharma in 1999.[10] In 2014, he was also one of the founders of the Marseille-Immunopole,[11][12][13] an immunology cluster linking fundamental research, therapeutic innovation, and industrial development in the Aix-Marseille region.

In addition to his academic activities, he became the chief scientific officer of Innate Pharma in January 2018. In 2022, he took over the presidency of the PSCC (Paris Saclay Cancer Cluster[5][4]), designated in December 2022 as the first winner of the "Biocluster" call for expressions of interest under the France 2030 program launched by the French government to promote investment, innovation and re-industrialization.[14] The PSCC's stated ambition is to position France among the world leaders in the field of cancer, transforming science into value for patients and society.

Scientific insights

Vivier has made contributions to the understanding of the molecular basis of the ontogeny, function, and therapeutic manipulation of natural killer (NK) cells,[15][16] and the identification of innate lymphoid cells (ILCs) in mice and humans.[17] His research has had a profound influence on the field of innate immunology.[18][19][20][21]

His early work had determined the mode of action of the inhibitory MHC class I receptors expressed on NK cells and extended the concept of ITIM-bearing molecules to multiple cell types and multiple biologic functions. In parallel, his group identified the ITAM-bearing polypeptide, KARAP/DAP12/Tyrobp.[22]

These studies on NK cells led to the involvement of the Vivier laboratory in the discovery of ILCs through the detection and characterization of the ILC3 cell subset in human and mouse intestines.

Vivier has published more than 300 scientific articles[23] and is on the editorial boards of leading peer-reviewed journals. He serves on the expert panel of the European Research Council and the committees of pharmaceutical and biotechnology companies.[24][25][26][27]

Awards and honours

  • The French National League against Cancer (1996, 2004, and 2013)[28]
  • The National Award and Tremplins Rhône-Poulenc Award for Biotech start-ups (1999)
  • The Lucien Tartois Award from the Fondation pour la Recherche Médicale (1999)[29]
  • The Jacques Oudin Award from the French Society for Immunology (2003)[30]
  • The Deutsche Gesellschaft für Immunologie/EFIS Award (2004)[31]
  • The Grand Prix Turpin in Oncology (2008)[32]
  • The Grand Prix Charles Oberling in Oncology (2010)[33]
  • The Australasian Society for Immunology, Visiting Speaker Programme Award (2015)
  • Thomson Reuters Highly Cited Researcher (2015;2016,2017) [34]

In 2007, Vivier became a senior fellow of the Institut Universitaire de France, and, in 2013, he was elected to the French National Academy of Medicine. 

In 2016, he was awarded honorary citizen of the city of Cassis, Chevalier de la Légion d’Honneur[35] and Ambassadeur de la ville de Marseille.[36]

Current positions

  • Professor of Immunology, Marseille Medical School and Assistance-Publique des Hôpitaux de Marseille (PU-PH Classe Exceptionnelle)
  • Head of the “NK cells and Innate Immunity” lab, CIML.
  • Head of the NK monitoring lab, Conception Hospital, Marseille.
  • Co-founder and coordinator of the Federation Hospitalo-Universitaire Marseille Immunopole.
  • Chief Scientific Officer and Senior Vice President of Innate Pharma.[2]
  • President of the Paris-Saclay Cancer Cluster.

References

  1. ↑ "Laboratoire d'immunologie - Hôpital de la Conception | AP-HM". fr.ap-hm.fr (in French). Retrieved 2018-01-11.
  2. 1 2 3 "Marseille : le Professeur Éric Vivier retrouve Innate Pharma".
  3. ↑ "Communauté : Marseille immunopôle". Marseille Immunopôle (in French). Retrieved 2018-01-11.
  4. 1 2 "Innovation | Paris Saclay Cancer Cluster". PSCC (in French). Retrieved 2023-01-10.
  5. 1 2 "Le Paris Saclay cancer cluster veut dynamiser la création de start-up françaises en oncologie". Le journal du Grand Paris - L'actualité du développement de l'Ile-de-France (in French). 2022-08-29. Retrieved 2023-01-10.
  6. ↑ "Eric Vivier - Who's Who". www.whoswho.fr (in French). Retrieved 2017-03-14.
  7. ↑ "Professor Eric Vivier - Centre d'Immunologie de Marseille-Luminy". Walter and Eliza Hall Institute of Medical Research. 2015-01-19. Retrieved 2017-03-14.
  8. ↑ "Cancer Immunology Research: 3 (10)". Cancer Immunology Research. 3 (10). 2015-10-01. ISSN 2326-6066.
  9. ↑ "APMnews - Le Pr Eric Vivier nommé directeur du Centre d'immunologie Marseille-Luminy". www.apmnews.com (in French). Retrieved 2018-01-11.
  10. ↑ "Founders | Innate Pharma". innate-pharma.com. Retrieved 2017-02-16.
  11. ↑ "Accueil : Marseille immunopôle". Marseille Immunopôle (in French). Retrieved 2017-02-16.
  12. ↑ "Immunopole : l'exception marseillaise". Le Monde.fr (in French). Retrieved 2017-03-14.
  13. ↑ "Cancer : la recherche française séduit les industriels étrangers". lesechos.fr. 2016-04-12. Retrieved 2017-03-14.
  14. ↑ "France 2030 : « Paris Saclay Cancer Cluster », premier lauréat de l'AMI « Biocluster »". enseignementsup-recherche.gouv.fr (in French). Retrieved 2023-01-10.
  15. ↑ "Que suis-je : la philo bouscule la biologie". Le Monde.fr (in French). Retrieved 2017-03-14.
  16. ↑ "Une cellule tueuse mutante à l'assaut des virus". Le Monde.fr (in French). Retrieved 2017-03-14.
  17. ↑ "Les cellules innées lymphoïdes: système de secours contre les infections de l'intestin". www.inserm.fr (in French). Archived from the original on 2017-03-11. Retrieved 2017-03-14.
  18. ↑ Huet, Sylvestre. "sciences.blogs.liberation.fr - Une piste pour booster l'immunité ? - Libération.fr". sciences.blogs.liberation.fr (in French). Retrieved 2017-03-14.
  19. ↑ "Ces drôles de pieuvres dans notre sang". Le Monde.fr (in French). Retrieved 2017-03-14.
  20. ↑ "Les tueuses de l'immunité innée". Pourlascience.fr (in French). Retrieved 2017-03-14.
  21. ↑ "Infections: Inactiver un gène pour stimuler le système immunitaire? – Inserm et Science –". 20 January 2012. Retrieved 2017-03-14.
  22. ↑ Tomasello, Elena; Vivier, Eric (2005-06-01). "KARAP/DAP12/TYROBP: three names and a multiplicity of biological functions". European Journal of Immunology. 35 (6): 1670–1677. doi:10.1002/eji.200425932. ISSN 1521-4141. PMID 15884055. S2CID 45371614.
  23. ↑ "Eric Vivier - Citations Google Scholar". scholar.google.fr. Retrieved 2017-03-14.
  24. ↑ "Eric Vivier".
  25. ↑ "Steering Committee: Antibodies for Medicine". www.mimabs.org. Retrieved 2017-03-14.
  26. ↑ "Comité Scientifique de la Fondation BMS pour la Recherche en Immuno-Oncologie". fondation-bms.fr (in French). Retrieved 2017-03-14.
  27. ↑ "Management - Bioaster". Bioaster. Retrieved 2017-03-14.
  28. ↑ "Prix DUQUESNE 2013 du Comité de Paris de la Ligue Nationale contre le Cancer". www.paca.inserm.fr (in French). Retrieved 2017-03-14.
  29. ↑ "Les prix de la fondation pour la recherche médicale" (PDF). Archived from the original (PDF) on 2016-03-03. Retrieved 2017-03-14.
  30. ↑ "Société Française d'Immunologie". www.sfi-immunologie.com.fr. Retrieved 2017-03-14.
  31. ↑ "EFIS – European Federation of Immunological Societies: EFIS-IL Lecture Award". www.efis.org. Retrieved 2017-03-14.
  32. ↑ "Prix René Turpin" (PDF).
  33. ↑ "Les membres - Institut Universitaire de France". www.iufrance.fr (in French). Retrieved 2017-03-14.
  34. ↑ "Awards" (PDF).
  35. ↑ "Eric Vivier est promu dans l'ordre de la Légion d'honneur au grade de chevalier | CIML". www.ciml.univ-mrs.fr. Retrieved 2017-03-14.
  36. ↑ "Les ambassadeurs – Accueil – ClubM". clubm.marseille.fr (in French). Retrieved 2017-03-14.
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