| FAM177A1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | FAM177A1, C14orf24, family with sequence similarity 177 member A1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | HomoloGene: 27852 GeneCards: FAM177A1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Family with sequence similarity 177 member A1 (FAM177A1) is a protein that in humans is encoded by the FAM177A1 gene, previously known as C14orf24.[3] The other member of this family is FAM177B.
Function
FAM177A1 has been linked to immune system regulation[4] and to neurogenesis.[5][6]
Interactions
IntAct reports physical interactions between FAM117A1 and these other human proteins:[7]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000151327 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "FAM177A1 family with sequence similarity 177 member A1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2022-08-24.
- ↑ Liao, Bo-Wei; Zhang, Hong-Yan; Du, Wen-Tian; Ran, Yong; Wang, Yan-Yi; Xu, Zhi-Sheng (2021-12-15). "FAM177A1 Inhibits IL-1β-Induced Signaling by Impairing TRAF6-Ubc13 Association". Journal of Immunology. 207 (12): 3090–3097. doi:10.4049/jimmunol.2100561. ISSN 1550-6606. PMID 34799425. S2CID 244428716.
- ↑ Ko, Hae Young; Lee, Dong Soo; Kim, Soonhag (2009-08-08). "Noninvasive imaging of microRNA124a-mediated repression of the chromosome 14 ORF 24 gene during neurogenesis". The FEBS Journal. 276 (17): 4854–4865. doi:10.1111/j.1742-4658.2009.07185.x. ISSN 1742-4658. PMID 19663910. S2CID 205881038.
- ↑ Alazami, Anas M.; Patel, Nisha; Shamseldin, Hanan E.; Anazi, Shamsa; Al-Dosari, Mohammed S.; Alzahrani, Fatema; Hijazi, Hadia; Alshammari, Muneera; Aldahmesh, Mohammed A.; Salih, Mustafa A.; Faqeih, Eissa; Alhashem, Amal; Bashiri, Fahad A.; Al-Owain, Mohammed; Kentab, Amal Y. (2015-01-13). "Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families". Cell Reports. 10 (2): 148–161. doi:10.1016/j.celrep.2014.12.015. ISSN 2211-1247. PMID 25558065.
- ↑ "IntAct Portal". www.ebi.ac.uk. Retrieved 2022-08-26.
External links
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