First Bank is the name used by various financial institutions worldwide. The term, either as whole or as part of a combination of names, may refer to:

International

• First Bank of Nigeria, a Nigerian bank with branches in Ghana, South Africa, Guinea, Gambia, Sierra Leone, DRC, UAE, United States, UK, France, China, etc.
• First National Bank (disambiguation), a name used by various banks worldwide
• First Interstate Bank (disambiguation), a name used by various banks worldwide
• First Commercial Bank (disambiguation), used by a bank in Taipei, Taiwan, as well as several in the United States

Africa

• First Bank of Nigeria, with branches across Nigeria
• Afriland First Bank, in Cameroon, Equatorial Guinea, Congo (Brazzaville) and Sao Tome e Principe

Asia

• First Gulf Bank, in Abu Dhabi, United Arab Emirates
• First Microfinance Bank, in Karachi, Sindh, Pakistan
• First Microfinance Bank, in Dushanbe, Tajikistan
• First Women Bank Limited, in Karachi, Sindh, Pakistan
• First Pacific Bank, a former bank based in Hong Kong

Europe

• First Bank, part of the J.C. Flowers & Co. Group, in Romania
• First Trust Bank, part of the AIB Group, in Belfast, Northern Ireland

United States

• FirstBank Holding Co, also known as 1stBank, a privately held bank based in Lakewood, Colorado with locations in Colorado, California, and Arizona
• First American National Bank, a defunct bank now part of Amsouth Bancorporation
• First Bancorp, a financial holding company in Southern Pines, North Carolina
• First BanCorp, more commonly known as FirstBank, a financial holding company in Puerto Rico
• First Bank & Trust, headquartered in Evanston, Illinois and serving the Chicago area
• First Bank System, a Minneapolis, Minnesota-based regional bank holding company that had used the trade name First Bank before the holding company was renamed U.S. Bancorp in 1997
• First International Bank, in Watford City, North Dakota
• First Midwest Bank, in Joliet, Illinois
• Seafirst Bank, acquired by Bank of America, known in the early 1970s as Firstbank
• Security First Network Bank, claimed to be the first pure internet bank, in Atlanta, Georgia

Caribbean

• FirstCaribbean International Bank, in Barbados
• FirstBank (Puerto Rico), in Puerto Rico, formerly First Federal

Similarly Named

• FirstBank Building, part of the Palmer Center complex, is a class A high-rise office building in Colorado Springs, Colorado. The building was known as the Holly Sugar Building
• First American Bank (disambiguation)
• First Commonwealth Bank, a financial services company based in Indiana, Pennsylvania, primarily serving the Western and the Central Pennsylvania regions
• First Federal Bank (disambiguation)
• First Pennsylvania Bank, a bank based in Philadelphia, Pennsylvania. Founded in 1782, it was for decades the oldest bank in the United States until it was acquired by CoreStates Financial Corporation in 1989
• First Security Bank, a privately held company based in Searcy, Arkansas
• First State Bank (disambiguation)
• First Westroads Bank, a locally owned community bank in Omaha, Nebraska, USA, with two branches

Other uses

• First Bank F.C., a Nigerian association football club run by First Bank of Nigeria