Jakob Mathias Antonson Lothe (14 November 1881 – 17 June 1975) was a Norwegian politician for the Liberal Party.

He was born in Lote in Gloppen as a son of farmers Anton Jakobsen Lothe (1852–1932) and Anne Marie A. Røsæt (1853–1940).^[1]

He was a member of Gloppen municipal council between 1919 and 1928, except for a short period between 1923 and 1925. He was elected to the Norwegian Parliament from Sogn og Fjordane in 1925, and was re-elected on five occasions, with a spell as deputy representative during the term 1928–1930.^[1] However, he served most of that term as well, after regular representative Per Klingenberg Hestetun died.

Lothe was President of the Lagting, the former quasi-upper house of the parliament of Norway, from 1945–1954.^[1]

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